“Hope is a practice. It comes from doing.” As the head of Planned Parenthood, Alexis McGill Johnson is regrouping in the wake of the U.S. Supreme Court’s decision to remove the federal right to safe abortion. Johnson is now faced with the challenge to move her team from tears and shock to action. Any leader faced with a worst-case scenario can learn from her vision: “to fight and stay courageous, and maintain ourselves.”

Volunteering and service are muscles that can close America’s divides and push social change. Speaking live at the 2022 Social Innovation Summit in Washington, D.C., AmeriCorps’ new CEO, Michael Smith, shares a vision for healing sociopolitical divides through partnerships and on-the-ground experiences. When it comes to tackling natural and social crises, he’s prioritizing impact over volume.

When a tech nonprofit competes against a $2 billion incumbent dominating the market, its odds are slim. But Zo Orchingwa took that bet, founding Ameelio, believing that access to communication and education for the incarcerated is needed for their future success. Ameelio is on a quest to partner with every prison district in the country until one day, it scales enough to be redundant.

While gasoline prices soar, solar company Sunrun is poised to usher in a customer-led revolution of distributed energy technologies. Sunrun’s CEO Mary Powell combats a “no and slow” culture to transform more homes into virtual energy plants by preaching optimism and scorning bureaucracy. She’s moving with urgency to create a cleaner and more cost-effective future as fast as possible.

A diverse network of collaborators is key when making scale leaps. Moderna CEO Stéphane Bancel has cultivated a wide network of scientists, business leaders, and government officials across his career. When COVID-19 struck, Bancel called upon this nexus of experts to aid the warp-speed development of the mRNA-based vaccine in the race to save millions of lives.

It’s easy to have a grand idea; putting that plan into action is not. Victoria Yampolsky conceived of a global concert in support of Ukraine. Without any experience in entertainment or international aid, she shares how she didn’t accept “no” for an answer in her quest to book big-name guests like Pink Floyd and negotiate a streaming deal — to pursue a fundraising goal of $10 million.

If you’re launching a moonshot, success depends on how you manage the trajectory of risk. When Stéphane Bancel became Moderna’s first CEO, the biotech start-up was chasing a way-out idea many experts thought was impossible. Stéphane built a culture of calculated risk-taking to create a platform for extraordinary leaps — one that enabled life-saving mRNA vaccines when Covid-19 struck.

We often hear the story about the great leader who joins a legacy company and guides it through massive transformation. But massive transformation can also start from the inside. Bill Ford, the executive chair of the Ford Motor Company, founded by his great-grandfather, is proof that great change can come from within. He has led not just one but multiple refreshes of Ford’s mission, culture, and, especially, their approach to sustainability. In Part One, you’ll hear about Bill Ford’s unusual entry into the family business.

Charity Dean was one of the first public health officials to set the alarm on COVID. When she searched for a tool to forecast future bio threats, she realized that it didn’t exist yet. So she co-founded the Public Health Company, where she uses lessons from her government experiences, but without the same rules or limits. She speaks with Bob Safian about why all companies must be public health companies.

Gayle Smith is the CEO of the ONE Campaign, the advocacy group founded by U2’s Bono — and last year, she was tapped by the U.S. State Department to coordinate America’s COVID response and vaccine distribution globally. Her experience both inside and outside government gives her a distinctive outlook on how business can and should help on humanitarian issues, from Ukraine dislocation to climate change. She also shares lessons about effective advocacy: tactics pioneered by ONE that can be useful to any organization trying to generate impact.

Amid pandemic disruption, Chief turned a small, NYC-based club for women executives into a national phenomenon with more than 12,000 members. Co-founder and CEO Carolyn Childers shares how she and co-founder Lindsay Kaplan managed the transformation, which recently yielded a $100 million Series B funding round for a whole new set of tools to support business leaders.

Your local community can be the power behind an epic scale story — because smart community investment always maximizes returns. In creating opportunities for new jobs, Chobani’s Hamdi Ulukaya created opportunities for massive scale.