Navigate today’s uncertain climate with a steadfast resolve. Recorded live at the Masters of Scale Summit in San Francisco, former Merck CEO Ken Frazier and Upwork CEO Hayden Brown talk with host Bob Safian about how leaders should trust their values when faced with social, political, and economic challenges. Brown shares how leading through the chaos of the pandemic brought new opportunities to increase diversity and productivity. Frazier details Merck’s reactionary strategy to the Russian invasion of Ukraine and offers clear advice to socially conscious leaders.

Can you build with conscience and still succeed? Mitch Kapor & Dr. Freada Kapor Klein certainly think so. As tech industry veteran founders and investors, Mitch and Freada have long embraced non-traditional metrics that put humans at the center. Mitch co-founded Lotus, the 1980s software giant, and hired Freada to help make the company “the most progressive employer in the U.S.” And years later, their early-stage VC firm, Kapor Capital, aligns their portfolio with their values, investing in companies that close gaps in access and opportunity. Human-centered metrics don’t just improve cultures — they improve the bottom line.

How do you balance saving capital versus taking advantage of current opportunities? How do investors and founders evaluate risk differently? And how do you embrace disruptive new technology without sending the message that you’re replacing humans with robots? Reid Hoffman and Bob Safian answer these questions and more, all posed in a special live Strategy Session by entrepreneurs across many industries and stages of scale. Plus Reid shares how playing games can revolutionize the way you strategize as a leader.

Rapid Response with Bob Safian: Can you truly take advantage of AI before speaking its language? Microsoft’s VP of Design and AI, Dr. John Maeda discusses AI’s common misconceptions and its misunderstood opportunities. A veteran of AI development, John shares valuable insights for entrepreneurs about how to engage with the new technology — from overcoming trepidation to making AI work harder for you — and AI’s potential to help leaders make better decisions.

Reid Hoffman and Bob Safian sit down once more to discuss how today’s hot-button stories are impacting business. And right now, there’s no hotter topic than ChatGPT and the race to bring transformative AI tools into the mainstream. So in this special AI deep-dive, Reid and Bob discuss how ChatGPT has reignited the search engine wars, how we can expect AI to transform our work and leisure, ways to see through the hype, and how business leaders should get the jump on the AI inflection point.

Reid Hoffman and Bob Safian answer questions posed live by entrepreneurs across many industries and stages of scale. Plus Reid reminds us the importance of staying grounded in our humanity amid the spate of big tech layoffs in our Need to Know segment.

For entrepreneurs and business leaders, the path to success is littered with traps. In this special episode of Masters of Scale, we go into the trenches with leaders from Google, Uber, LinkedIn, and more for inside stories on how to identify, decode, and surmount unexpected pitfalls — from organizational jams to overcommunication, from bloated meetings to bungled succession planning. Learn how to get out of, and avoid, these traps, for yourself and the entire organization.

All great teams need to improvise under pressure, but underpinning this should be a set of tried-and-tested playbooks that let you orchestrate and replicate winning strategies. Cisco’s John Chambers created a library of living playbooks — covering culture, acquisitions, crises, and more — to astounding effect as he took Cisco from a small tech supplier to the most valuable company on the planet.

Reid Hoffman and Bob Safian sit down once more to discuss how today’s hot-button stories are impacting business. The co-hosts address the key trends that all entrepreneurs should be up to speed on, from the travails of Twitter to the triumphant return of Bob Iger. Featuring PepsiCo’s Mauro Porcini, CNBC’s Julia Boorstin, and Color of Change’s Rashad Robinson.

Taking risks can be the catalyst for immense scale or dire straits. Avoiding taking any risks at all leads to stagnancy and empowered competitors. The key is to know which risks are worth taking, and when and how to take them. This episode highlights the best conversations we’ve had recently about taking advantage of risk and how fortune favors the brave.

Building a business means making mistakes. Lots of them. But how you’re wrong isn’t always obvious. Jack Conte has learned this lesson as a working musician — and while scaling Patreon into a company worth $4b. In Part One of a two-part series, you’ll hear how Jack wrote his own Wrongness Playbook, as he learned to answer questions like: If something isn’t working, is it time to trust your instincts? Or is there critical feedback you’ve been ignoring?

Amazon wants to get bigger, but with that scale comes great responsibility. So says Adam Selipsky, CEO of Amazon Web Services, the most profitable and fastest growing part of the tech giant. Selipsky, who also oversees Amazon’s climate change efforts, points to two additions to the company’s vaunted “Leadership Principles” as evidence of Amazon’s commitment. Arguing that AWS is still in early days, he shares what he’s hearing from other CEOs about their biggest concerns, why “carbon intensity” is the best measure of climate progress for businesses, and what Amazon’s aspiration to be “Earth’s best employer” really means.