Reid Hoffman shares the inside story of his bold new venture to disrupt cancer drug development: Manas AI.

Host Jeff Berman joins Mike and Kass Lazerow on stage at SXSW to discuss their extraordinary career journey as co-founders and spouses.

Shan-Lyn Ma shares how intrapreneurship prepared her to build a business that’s transformed the wedding industry with online tools.

Discover how the co-founders of Sweetgreen scaled the business — in alignment with its core values — to a public company valued at $2.5 billion.

Reid Hoffman welcomes the newest host of Masters of Scale, Jeff Berman, for a dialogue that digs into a re-founder’s mission: evolving an organization while staying true to core values.

As we settle into 2024, the Masters of Scale team reflect on their favorite moments from the past year.

Elan Lee reveals how he cultivated a community around Exploding Kittens by transforming casual colleagues, partners, and customers into key stakeholders.

Celebrated filmmaker Ron Howard has a remarkable ability to maintain his vision of creating captivating and deeply human stories — while strengthening how he delivers this vision by incorporating changes in technology, audience tastes, and styles of filmmaking.

In part 2 of this episode with veteran founders and investors Mitch Kapor & Dr. Freada Kapor Klein, we get into the data of building human-centered cultures. In part one, we heard how Mitch and Freada went all-in on investing their values, committing 100% of new investments in “gap-closing” companies that aim to improve society, even as they aim for scale and liquidity as well. Now, Mitch and Freada can share how that’s played out in practice, with both positive examples … and some negative ones as well. (Yes, they were early investors in Uber!)

Can you build with conscience and still succeed? Mitch Kapor & Dr. Freada Kapor Klein certainly think so. As tech industry veteran founders and investors, Mitch and Freada have long embraced non-traditional metrics that put humans at the center. Mitch co-founded Lotus, the 1980s software giant, and hired Freada to help make the company “the most progressive employer in the U.S.” And years later, their early-stage VC firm, Kapor Capital, aligns their portfolio with their values, investing in companies that close gaps in access and opportunity. Human-centered metrics don’t just improve cultures — they improve the bottom line.

Running a business can be a lonely job. The long hours, the existential threats — it can feel like the weight of the entire company is on your back. That’s where the transformative power of co-founders comes in. Co-founders provide more than added manpower; they bring fresh perspectives and talents that help businesses conquer problems at speed. And the co-founder effect extends beyond the people who started the company: The lessons hold true for every team member that contributes in a foundational way. The more voices you add, the more resilience you build in yourself, and your organization.

What can an entrepreneur learn from a world-class musician? How to create a world-class team, and unite around a clear mission. In this special crossover episode with our sister podcast, Spark & Fire, you’ll hear world-renowned cellist Yo-Yo Ma tell the story of co-founding The Silk Road Project — a musical collective that brings together musicians from wildly different traditions to write and perform original music.