Building a business means making mistakes. Lots of them. But how you’re wrong isn’t always obvious. Jack Conte has learned this lesson as a working musician — and while scaling Patreon into a company worth $4b. In Part One of a two-part series, you’ll hear how Jack wrote his own Wrongness Playbook, as he learned to answer questions like: If something isn’t working, is it time to trust your instincts? Or is there critical feedback you’ve been ignoring?

How can small businesses survive in times of volatility? How should an entrepreneur balance limited resources with big ambitions? Reid Hoffman and Bob Safian answer questions from small business owners in the Masters of Scale community. Plus: another round of Pivot Point, and a Need to Know segment.

The fallout from the pandemic is proving to be as challenging for business leaders to navigate as the pandemic’s onset. Target’s CEO Brian Cornell had to make difficult decisions in the second quarter of this year to manage an unexpected surplus of goods and home technology. He shares his most recent learnings, as well as lessons for handling skepticism, the need for agility, and why mental wellness is key to a successful team.

If you’re a leader right now navigating the global pandemic, supply chain disruptions, and your own mental list of what’s keeping you up at night, the issue of burnout is probably on your mind. You can’t shield your team from all stress, but you can find effective ways of supporting your employees through it. This episode highlights the best conversations we’ve had recently about stopping burnout in your organization, before it takes hold.

Featuring BetterUp’s Alexi Robichaux, Upwork’s Hayden Brown, Merck’s Ken Frazier, Chobani’s Hamdi Ulukaya, director J.J. Abrams, Girls Who Code’s Reshma Saujani, BW4BL’s Tokunbo Koiki, and FuelFinance’s Alyona Mysko.

Crypto winter isn’t a disaster, it’s an opportunity. That’s how Michael Gronager, CEO of $8 billion crypto data company Chainalysis, describes the crashing prices and bankruptcies that have roiled the cryptocurrency sector. Gronager offers an insider’s perspective on operating in a volatile marketplace, providing lessons on dreaming too big in boom times and on leaning into building and creating when lulls emerge. Chainalysis helps track financial flows on blockchains, including crypto criminals from North Korea and Russia. Despite current risks, Gronager argues, the still-emerging crypto sector is maturing, and he’s as confident as ever about its future.

Reid Hoffman and Bob Safian sit down to discuss how today’s hot-button stories are impacting business. The co-hosts address the key trends that all entrepreneurs should be up to speed on, from the looming recession and cryptocurrency’s possible demise to the hybrid workplace and moral leadership. Featuring Mercy Corps’ Tjada McKenna, PwC’s Tim Ryan, and Girls Who Code’s Reshma Saujani.

“Hope is a practice. It comes from doing.” As the head of Planned Parenthood, Alexis McGill Johnson is regrouping in the wake of the U.S. Supreme Court’s decision to remove the federal right to safe abortion. Johnson is now faced with the challenge to move her team from tears and shock to action. Any leader faced with a worst-case scenario can learn from her vision: “to fight and stay courageous, and maintain ourselves.”

What’s the difference between an activist brand and an active brand? Impossible Foods CEO Peter McGuinness says that acting on your values defines a business — from climate change to Roe v. Wade. To unleash the next wave of growth for plant-based meat purveyor Impossible, McGuiness is rethinking how the whole category presents itself, taking aim at what he calls “safe and lame” approaches, partnering with the likes of Billie Eilish, and targeting the $1.4 trillion global meat industry.

Volunteering and service are muscles that can close America’s divides and push social change. Speaking live at the 2022 Social Innovation Summit in Washington, D.C., AmeriCorps’ new CEO, Michael Smith, shares a vision for healing sociopolitical divides through partnerships and on-the-ground experiences. When it comes to tackling natural and social crises, he’s prioritizing impact over volume.

Most future of work conversations revolve around the “where,” but Upwork CEO Hayden Brown says it’s more important to focus on the “who.” 10% of the workforce at Upwork, the global tech platform for millions of freelance workers, was directly impacted by the war in Ukraine. Hayden’s people-focused approach to the difficult decision of how to manage remote employees there and in Russia is the same mindset she applies to meet the needs of all workers, from people feeling conflict to working mothers.

Entrepreneurship is an essential tool for building a more equitable society — which is why Kathryn Finney is laser-focused on encouraging people who don’t fit the mold of the stereotypical founder to jump in. Her new book, “Build the Damn Thing,” taps into wisdom from her years at the venture studio Genius Guild and beyond. She brings a message to founders: The universe is conspiring for your greatness.

If you’re launching a moonshot, success depends on how you manage the trajectory of risk. When Stéphane Bancel became Moderna’s first CEO, the biotech start-up was chasing a way-out idea many experts thought was impossible. Stéphane built a culture of calculated risk-taking to create a platform for extraordinary leaps — one that enabled life-saving mRNA vaccines when Covid-19 struck.