Small, independent store owners have been perpetually hit by waves of disruption: from malls to big box stores to e-commerce giants. But Max Rhodes, co-founder and CEO of the $12 billion online wholesale marketplace Faire, argues that Main Street retailers are actually better positioned right now to navigate today’s stormy shopping landscape than the competition. Max digs into how Faire is using technology and data to help stores maximize their advantages — nimbleness, adaptability, and smaller inventories — and combine them with the scale benefits enjoyed by the likes of Amazon and Target.

Reid Hoffman and Bob Safian sit down once more to discuss how today’s hot-button stories are impacting business. The co-hosts address the key trends that all entrepreneurs should be up to speed on, from the travails of Twitter to the triumphant return of Bob Iger. Featuring PepsiCo’s Mauro Porcini, CNBC’s Julia Boorstin, and Color of Change’s Rashad Robinson.

Innovation is the lifeblood of the start-up — from product to processes and culture to creativity. But innovation is just as essential for scale companies. So how do you keep the innovation flywheel spinning at all levels of scale? The answer according to Linda Yates is to seed every level of your company with an intrapreneurial mindset. As CEO of Mach49, an incubator for large global companies, Linda shares her vast experience and strategies for injecting intrapreneurial thinking and bias-to-action across hundreds of large-scale organizations.

Hybrid, remote, in-person, a little bit of everything? Work has transformed into a giant experiment. Priya Parker, expert facilitator and author of The Art of Gathering: How We Meet and Why It Matters, shares her advice on how to manage the new hybrid workplace. Where to start? Focus first, she suggests, on making your meetings better.

After slashing his NYC restaurant team from 2,400 people to just 45 in the teeth of the pandemic, Danny Meyer has rebuilt Union Square Hospitality Group back to its former size. But in his fifth appearance on Rapid Response since Covid struck, Danny says he isn’t yet triumphant. With inflation creating fresh challenges even at Shake Shack, Danny shares lessons on the good and bad of leading through a crisis, plus explains why he’s handed off his CEO title — and where he finds inspiration to fuel new innovations.

For truly sustainable long-term growth, you must prioritize your mission over your product — even if that means letting your product go. Noom founder and CEO Saeju Jeong has repeatedly turned his back on successful products in the name of his mission to help as many people as possible live healthier lives. In this episode, Saeju brings to life many of these make-or-break moments, and how his dedication to mission has driven his scale journey.

Can a small entrepreneur make an impact within a massive, complex system, like healthcare or education? What’s the best framework to amplify the positive side of having co-founders and avoid the negatives? Reid Hoffman and Bob Safian answer these and more questions from small business owners in the Masters of Scale community. Plus: in our Need to Know segment, Reid & Bob take on a burning question: How can Black founders beat the odds and find funding?

Too many businesses and organizations spend time planning and not enough in action, especially in times of emergency. José Andrés, world-famous chef and founder of the nonprofit World Central Kitchen, proves the value of fast action through his work, including his recent time in Ukraine serving over 150 million meals. José thinks businesses should flatten their power structure and treat food as a national security issue, even in places like the U.S.

The fallout from the pandemic is proving to be as challenging for business leaders to navigate as the pandemic’s onset. Target’s CEO Brian Cornell had to make difficult decisions in the second quarter of this year to manage an unexpected surplus of goods and home technology. He shares his most recent learnings, as well as lessons for handling skepticism, the need for agility, and why mental wellness is key to a successful team.

Reid Hoffman and Bob Safian sit down to discuss how today’s hot-button stories are impacting business. The co-hosts address the key trends that all entrepreneurs should be up to speed on, from the looming recession and cryptocurrency’s possible demise to the hybrid workplace and moral leadership. Featuring Mercy Corps’ Tjada McKenna, PwC’s Tim Ryan, and Girls Who Code’s Reshma Saujani.

While gasoline prices soar, solar company Sunrun is poised to usher in a customer-led revolution of distributed energy technologies. Sunrun’s CEO Mary Powell combats a “no and slow” culture to transform more homes into virtual energy plants by preaching optimism and scorning bureaucracy. She’s moving with urgency to create a cleaner and more cost-effective future as fast as possible.

If you’re launching a moonshot, success depends on how you manage the trajectory of risk. When Stéphane Bancel became Moderna’s first CEO, the biotech start-up was chasing a way-out idea many experts thought was impossible. Stéphane built a culture of calculated risk-taking to create a platform for extraordinary leaps — one that enabled life-saving mRNA vaccines when Covid-19 struck.