Skip to Content

Rebooting global crisis response


Gayle Smith is the CEO of the ONE Campaign, the advocacy group founded by U2’s Bono — and last year, she was tapped by the U.S. State Department to coordinate America’s COVID response and vaccine distribution globally. Her experience both inside and outside government gives her a distinctive outlook on how business can and should help on humanitarian issues, from Ukraine dislocation to climate change. She also shares lessons about effective advocacy: tactics pioneered by ONE that can be useful to any organization trying to generate impact.


“ONE’s approach meshes attention-getting initiatives with sophisticated policy — a double-edged weapon that works at places like the State Department as well as in the marketplace.”